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The McKittrick-Wheelock syndrome: A rare case with a complex acid-base disorder

Pietro Formagnana, Marianna Piombo, Costanza Caccia Dominioni, Giulia Gori, Michele Santoro, Ivo Casagranda
  • Marianna Piombo
    Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
  • Costanza Caccia Dominioni
    Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
  • Giulia Gori
    Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
  • Michele Santoro
    Emergency Department, General Hospital Cardinale Panico, Tricase, Italy
  • Ivo Casagranda
    Specialization School of Internal Medicine, University of Pavia, Pavia, Italy

Abstract

McKittrick-Wheelock syndrome is a rare condition characterized by secretory diarrhea due to villous adenoma of the colon, acute renal failure, dehydration, electrolyte and acid-base disorders. Diagnosis requires high suspicion especially when the presentation is unusual. Although potentially fatal for its complications, if promptly diagnosed and treated it is completely reversible. We present a case of a 67-year-old man who presented with syncope and diarrhea. On admission arterial blood gas test showed a complex acid-base disorder that led clinicians to further investigations and to point out a correct diagnosis.

Keywords

McKittrick-Wheelock syndrome; Metabolic alkalosis; Mucinous diarrhea; Electrolyte disorders.

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Submitted: 2018-07-18 09:33:26
Published: 2018-09-03 10:37:30
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Copyright (c) 2018 Pietro Formagnana, Marianna Piombo, Costanza Caccia Dominioni, Giulia Gori, Michele Santoro, Ivo Casagranda

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