Anaemia, thrombocytopenia and skin lesions


https://doi.org/10.4081/ecj.2022.10498
Vol. 18 No. 2 (2022)
Published: 27 June 2022
Skin lesions, paraneoplastic pemphigus, haematology
Abstract Views: 864
PDF: 153
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Authors

  • Erika Poggiali
    poggiali.erika@gmail.com
    Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy.
  • Giorgio Orofino Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
  • Jacopo Peccatori Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

A 73-year-old man affected by hyperuricemia, dyslipidaemia and hypothyroidism presented to the emergency room with a 3-month history of fever, exertional dyspnea, progressive asthenia, and painless not itchy skin lesions. Physical exam showed purplish papules and plaques affecting any area of his body, and a slight bilateral oedema of his legs. Laboratory studies revealed a severe macrocytic anaemia (haemoglobin 4.8 g/dL, mean cell volume 119 fL) and thrombocytopenia (34,000/mm3) with hyperferritinemia (1894 ng/mL, normal value <400) and increased serum B12 (1412 pg/mL, normal value 197-771), associated with ESR 71 mm/h (normal value 1-15), CRP 139 mg/L (normal value <6), and procalcitonin 1.05 ng/mL (normal value <0.5).


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Poggiali, E., Orofino, G., & Peccatori, J. (2022). Anaemia, thrombocytopenia and skin lesions. Emergency Care Journal, 18(2). https://doi.org/10.4081/ecj.2022.10498

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