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Tc99m-HMPAO white blood cell scintigraphy: added value of SPECT/CT for infection diagnosis in cardiothoracic surgery

Napoleone Prandini, Stefano Panareo, Rosario Cultrera, Chiara Peterle, Valentina de Cristofaro, Massimo Roncali, Vincenzo de Biasi, Lorenzo Badia, Luciano Feggi
  • Napoleone Prandini
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy | s.panareo@ospfe.it
  • Stefano Panareo
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy
  • Rosario Cultrera
    Infectious and Tropical Disease Section, University of Ferrara, Italy
  • Chiara Peterle
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy
  • Valentina de Cristofaro
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy
  • Massimo Roncali
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy
  • Vincenzo de Biasi
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy
  • Lorenzo Badia
    Infectious and Tropical Disease Section, University of Ferrara, Italy
  • Luciano Feggi
    Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy

Abstract

We report a case of a woman who came to our attention because of fever and a sternal fistula draining purulent fluid. Four years before, she had undergone cardiothoracic surgery to place a patch because of a myocardial rupture. Under suspicion of a deep mediastinal infection, a Tc99m-HMPAO white blood cell (WBC) scintigraphy was performed. The use of planar imaging and single photon emission computed tomography (SPECT/CT) imaging allowed the identification of a sternal infection, which involved the anterior mediastinum up to pericardium and diaphgram. SPECT/CT led to a precise diagnosis of a thoracic infection, providing the location and extent of the disease. This turned out useful to improve therapeutic strategies.

Keywords

SPECT/CT, Tc99m-HMPAO white blood cell scintigraphy, cardiothoracic surgery.

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Submitted: 2011-09-27 10:26:40
Published: 2012-02-03 17:36:11
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Copyright (c) 2012 Napoleone Prandini, Stefano Panareo, Rosario Cultrera, Chiara Peterle, Valentina de Cristofaro, Massimo Roncali, Vincenzo de Biasi, Lorenzo Badia, Luciano Feggi

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