Diagnosis of neurofibromatosis type 1 after resection of intercostal nerve neurofibroma


Submitted: 2 September 2011
Accepted: 2 May 2012
Published: 24 May 2012
Abstract Views: 2856
PDF: 952
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Borja Aguinagalde Department of Thoracic Surgery, Donostia Hospital, Donostia-San Sebastian, Spain.
  • Jon Zabaleta Department of Thoracic Surgery, Donostia Hospital, Donostia-San Sebastian, Spain.
  • Marta Fuentes Department of Thoracic Surgery, Donostia Hospital, Donostia-San Sebastian, Spain.
  • Nerea Bazterargui Department of Thoracic Surgery, Donostia Hospital, Donostia-San Sebastian, Spain.
  • Carmen Lobo Department of Pathology, Donostia Hospital, Donostia-San Sebastian, Spain.
  • José Miguel Izquierdo Department of Thoracic Surgery, Donostia Hospital, Donostia-San Sebastian, Spain.
We report a case of a 37-year-old man with an asymptomatic extraparenchymal mass in the left hemithorax. Complete surgical removal of the tumour was achieved through a minithoracotomy and histological analysis confirmed the diagnosis of myxoid neurofibroma. Given this histological diagnosis, the patient was re-examined and many café au lait spots (more than 6, larger than 15 mm in diameter) and neurofibromas (elastic tissue) were observed and the patient was diagnosed with neurofibromatosis (NF) type 1 (von Recklinghausen’s disease). We have found only eight case reports of neurogenic tumours originating from an intercostal nerve; only two of these corresponded to neurofibromas. Among these two patients, only one was a case of NF type 1 and, in contrast to our case, the diagnosis was reached prior to surgery. We present a very rare case of intercostal nerve neurofibroma leading to a definitive diagnosis of NF type 1.

Aguinagalde, B., Zabaleta, J., Fuentes, M., Bazterargui, N., Lobo, C., & Izquierdo, J. M. (2012). Diagnosis of neurofibromatosis type 1 after resection of intercostal nerve neurofibroma. Chest Disease Reports, 2(1), e10. https://doi.org/10.4081/cdr.2.196

Downloads

Download data is not yet available.

Citations