Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis

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Giuseppe Limongelli
Emanuele Monda *
Giovanbattista Capozzi
Martina Caiazza
Maria Giovanna Russo
(*) Corresponding Author:
Emanuele Monda | emanuelemonda@me.com


Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.


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