Role of ventricular tachycardia ablation in arrhythmogenic right ventricular cardiomyopathy

  • Alberto Cipriani Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.
  • Riccardo Bariani Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.
  • Manuel De Lazzari Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.
  • Federico Migliore Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.
  • Carlo Angheben Division of Cardiology, Santa Maria del Carmine Hospital, Rovereto (TN), Italy.
  • Maurizio Del Greco Division of Cardiology, Santa Maria del Carmine Hospital, Rovereto (TN), Italy.
  • Domenico Corrado | domenico.corrado@unipd.it Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.
  • Alessandro Zorzi Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy.

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by progressive fibro-fatty replacement of the myocardium that represents the substrate for recurrent sustained ventricular tachycardia (VT). These arrhythmias characterize the clinical course of a sizeable proportion of patients and have significant implications for their quality of life and long-term prognosis. Antiarrhythmic drugs are often poorly tolerated and usually provide incomplete control of arrhythmia relapses. Catheter ablation is a potentially effective strategy to treat frequent VT episodes and ICD shocks in ARVC patients. The aims of this review are to discuss the electrophysiological and electroanatomic substrates of ventricular tachycardia in patients with ARVC and to analyze the role of catheter ablation in their management with particular reference to selection of patients, technical issues, potential complications and outcomes.

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Published
2017-11-07
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Section
Review Articles
Keywords:
Endocardial voltage mapping, electrophysiology, ventricular tachycardia, sudden death.
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How to Cite
Cipriani, A., Bariani, R., De Lazzari, M., Migliore, F., Angheben, C., Del Greco, M., Corrado, D., & Zorzi, A. (2017). Role of ventricular tachycardia ablation in arrhythmogenic right ventricular cardiomyopathy. Cardiogenetics, 7(1). https://doi.org/10.4081/cardiogenetics.2017.6882