Anti-aging and anti-tumor effect of FPP® supplementation


Submitted: 19 February 2020
Accepted: 29 February 2020
Published: 1 April 2020
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Authors

  • Mariantonia Logozzi Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Rossella Di Raimo Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Davide Mizzoni Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Stefano Fais Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

The beneficial effect of FPP® as antioxidant is known. Here we summarize recent data supporting future implementation of FPP® in tumor treatment and in controlling aging at the molecular level. We first showed that oral FPP® is able to control tumor growth and with inducing a potent and systemic anti-oxidant reaction (i.e. reduced ROS and increased GSH and SOD-1). Then we showed that FPP® is able to markedly increase the body anti-oxidant reaction together with increasing both telomerase activity in the blood and the telomeres length in bone marrow and ovary of treated mice as compared to the untreated mice.


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