Archivio Italiano di Urologia e Andrologia 2020-07-02T20:53:45+00:00 Emanuela Fusinato Open Journal Systems <p>The <strong>Archives of Italian Urology and Andrology</strong> publishes papers dealing with the urological, nephrological and andrological sciences. <em>Original Articles</em> on both clinical and research fields, <em>Reviews</em>, <em>Editorials</em>, <em>Case Reports</em>, <em>Abstracts </em>from papers published elsewhere, <em>Book Reviews</em>, <em>Congress Proceedings</em> can be published.</p> Paraurethral cyst in a newborn 2020-07-02T20:53:43+00:00 Raziye Ergun Duran Yildiz Cagri Akin Sekerci Hasan Kahveci <p>Paraurethral cysts are rare and occur with obstruction of the Skene duct. In this case, we aimed to present a paraurethral cyst in a baby girl. A 4-day-old newborn was consulted for pediatric urology because of an interlabial mass. In genital examination, a noninvasive mass measuring 2 × 1.5 cm was observed in the interlabial region, and the introitus was completely closed. Ultrasonography showed a cystic lesion localized on the right side of the urethra with a smoothly contoured, thin-walled, hypoechoic structure. The patient underwent puncture under sterile conditions. The content of the mass was mucoid and clear fluid. Paraurethral cysts are often asymptomatic and benign. There is no definitive consensus on treatment.</p> 2020-06-24T09:35:27+00:00 ##submission.copyrightStatement## Protective effect of chlorogenic acid on renal ischemia/reperfusion injury in rats 2020-07-02T20:53:44+00:00 Tuncay Toprak Cagri Akin Sekerci Hasan Riza Aydın Mehmet Akif Ramazanoglu Fatma Demet Arslan Banu Isbilen Basok Hatice Kucuk Huseyin Kocakgol Hamit Zafer Aksoy Seyhan Sumeyra Asci Yılören Tanıdır <p>Objectives: Ischemia/reperfusion (I/R) injury is a common cause of renal injury and to date, many pharmacological agents have been identified to decrease I/R injury. One of the potential compound that can target I/R injury is chlorogenic acid (CGA). It has potent antiinflammatory, antibacterial, anti-oxidant, analgesic and antipyretic activities in in vitro experiments and in vivo animal models. The aim of the study was to investigate the protective characteristic of CGA on renal I/R injury. <br>Material and Methods: 24 rats were randomly allocated to three groups (n = 8): Sham, I/R+CGA and I/R groups. CGA was administered intraperitoneally at a dose of 20 mg/kg, 10 min before reperfusion. I/R injury was achieved by clamping the left renal artery for 45 minutes, followed by reperfusion for 4 hours. The left kidneys of the rats were examined for tissue damage by histopathological and biochemical examination. For histological evaluation, EGTI scoring system was used. For biochemical examination total oxidant status, total antioxidant status and oxidative stress index were used. The power analysis indicated that 8 subjects per group would be required to produce 80% chance of achieving statistical significance at p &lt; 0.05 level. The results are expressed as mean ± SD. Mann- Whitney U was performed for statistical analysis. <br>Results: Histopathological examination of the tissue damage revealed that all kidneys in the sham group were normal. I-R group had significantly higher histopathological scores than other groups. Histopathological improvement was seen after CGA treatment. TAS, TOS and OSI values of I-R group were significantly higher than sham group (0.88 vs 0.76 (p: 0.004), 13.8 vs 7.04 (p: 0.021) and 0.15 vs 0.09 (p: 0.034), respectively). In CGA treated group TAS, TOS and OSI levels were 0.84, 6.47 and 0.07, respectively. CGA treatment resulted in significant improvement in TOS and OSI parameters. <br>Conclusions: CGA treatment provided marked improvement in renal histology and suppressed oxidative stress. Thus, CGA may have a protective effect in renal tissue against I/R injury.</p> 2020-06-24T09:26:19+00:00 ##submission.copyrightStatement## Comparison of the efficiency, safety and pain scores of holmium laser devices working with 20 watt and 30 watt using in retrograde intrarenal surgery: One center prospective study 2020-07-02T20:53:45+00:00 Sercan Sari Mehmet Çaglar Çakici Ibrahim Güven Kartal Volkan Selmï Harun Özdemïr Hakkı Ugur Ozok Ahmet Nihat Karakoyunlu Serkan Yildiz Emre Hepsen Serra Ozbal Hamit Ersoy hamitersoy@gmail.comm <p>Objectives: Holmium:Yttrium Aluminum Garnet laser lithotripsy is used in Retrograde Intrarenal Surgery. Fragmentation is made with a certain value of pulse energy (Joule) and frequency (Hertz) in Holmium laser lithotripsy and the multiplication of these values gives us total power (Watt). Devices with maximum power of 20 Watt and 30 Watt are used in clinical practice. We want to compare the efficiency, safety and pain scores of the lithotripsy made below 20 Watt and over 30 Watt with 30 Watt laser device. <br>Materials and methods: 60 patients who had 2-3 cm sized kidney stones and operation planned were prospectively divided into three groups. Groups were random identified. In the first group, fragmentation was performed below 20 Watt power with 20 Watt laser device. In the second group, fragmentation was performed below 20 Watt power with 30 Watt laser device. In the third group, fragmentation was performed over 20 Watt power with 30 Watt laser device. Demographic, stone, intraoperative and postoperative data were recorded. We compared these groups regarding efficiency, safety and pain score.<br>Results: For demographic and stone data, there was a statistically significant difference only for stone number. For intraoperative and postoperative data, there was a statistically significant difference only for ureteral access sheath usage between the groups. Success was lower than the other groups in Group 1.<br>Conclusions: Success was higher in groups using 30 Watt laser device. There was not statistically significantly difference between complications and pain. 30 Watt laser device is safe and efficient in Retrograde Intrarenal Surgery.</p> 2020-06-24T09:04:35+00:00 ##submission.copyrightStatement##