TY - JOUR AU - Abate, Danilo AU - Giusti, Giuseppe AU - Caria, Nicola AU - De Vita, Giuseppe AU - Lucci Chiarissi, Marco AU - De Lisa, Antonello PY - 2018/06/30 Y2 - 2024/03/29 TI - Skin flap squamous cell carcinoma developed after urethroplasty JF - Archivio Italiano di Urologia e Andrologia JA - Arch Ital Urol Androl VL - 90 IS - 2 SE - Case Reports - Oncology DO - 10.4081/aiua.2018.2.141 UR - https://www.pagepressjournals.org/aiua/article/view/aiua.2018.2.141 SP - 141-142 AB - Objectives: To describe our experience in diagnosis and treatment of urethral carcinoma following urethroplasty with a Orandi penile skin flap. <br />Material and methods: Our patient underwent to Orandi penile skin flap urethroplasty then developed a urethral epidermoid carcinoma on the flap approximately 15 years later. We treated this case with a partial penectomy surgery and perineostomy. Surgery was followed by chemotherapy with cisplatin and 5-fluorouracil. The progression of the disease led to a salvage surgery of total penectomy and asportation of testicles and scrotum.<br />Results: Despite the success of the surgery, the disease progressed and three months after the last surgical operation the patient died. <br />Conclusions: Urethral carcinoma on skin flap is a rare complication of the urethroplasty surgery but with severe consequences, so we recommend to undertake a long-term urological follow up in patients undergone such kind of surgery. ER -