2026. 21 | The role of prebiotic and probiotic supplementation in the prevention of clostridioides difficile infection: E. Cortese1, E. Del Giudice2, M. Ceci2, A. Cavalli2, U.G. Galasso1, G. Desideri1, L. Palleschi2 | 1Department of Internal Medicine and Medical Specialties, UOC Geriatrics, Sapienza University of Rome, Rome; 2Unit of Geriatrics, Medical Department, San Giovanni-Addolorata Hospital, Rome. Geriatric Care. 12, s1 (Jun. 2026). DOI:https://doi.org/10.4081/gc.2026.15772.