Reviews - Prostate
Vol. 86 No. 4 (2014)
https://doi.org/10.4081/aiua.2014.4.314

Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance

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Received: 23 January 2015
Published: 30 December 2014
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Prostate cancer, Prostate biopsy, Active surveillance, Tumour extent, Immunohistochemistry

Authors

Roberta Mazzucchelli
Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
Andrea Benedetto Galosi
Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
Antonio Lopez-Beltran
Department of Surgery, Cordoba University Medical School, Cordoba, Spain.
Marina Scarpelli
Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
Liang Cheng
Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Rodolfo Montironi
r.montironi@univpm.it
Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
Active surveillance (AS) is an important management option for men with lowrisk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts become mature. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and accurately reported by pathologists. Repeated biopsy after initial diagnosis of prostate cancer is recommended before inclusion in active surveillance for early detection of significant cancer.

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Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance. (2014). Archivio Italiano Di Urologia E Andrologia, 86(4), 314-318. https://doi.org/10.4081/aiua.2014.4.314

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