Sudden sensorineural hearing loss: role of hyperbaric oxygen therapy


Submitted: 19 December 2016
Accepted: 18 January 2017
Published: 24 February 2017
Abstract Views: 1688
PDF: 697
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Authors

  • Filippo Ricciardiello Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Teresa Abate Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Annalisa Pianese Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Massimo Mesolella Otorhinolaryngology Unit, University of Naples Federico II, Naples, Italy.
  • Flavia Oliva Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Pierpaolo Ferrise Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Giuseppe Cortese Department of Anesthesiology, Intensive Care, Hyperbaric Therapy and Pain Therapy, University of Naples Federico II, Naples, Italy.
  • Mariano Marmo Hyperbaric Medic Center, Department of Anesthesiology, Cardarelli Hospital, Naples, Italy.
  • Romolo Villani Hyperbaric Medic Center, Department of Anesthesiology, Cardarelli Hospital, Naples, Italy.
  • Marianna Abate Department of Biochemistry, Biophysics and General Pathology, University of Campania “L. Vanvitelli”, Naples, Italy.
  • Salvatore Mazzone Otorhinolaryngology Unit, Cardarelli Hospital, Naples, Italy.
  • Michele Cavaliere Otorhinolaryngology Unit, University of Naples Federico II, Naples, Italy.
Sudden sensorineural hearing loss is defined as an acute hearing reduction of 30 dB or more, in at least three consecutive frequencies, occurring within 3 days of symptom onset. There is no consensus on the best treatment option. The aims of this paper were to evaluate the effectiveness of a treatment protocol based on medical therapy combined with hyperbaric oxygen therapy and to examine the factors that influence the recovery of hearing (age, gender, the amount of time between the onset of symptoms and the initiation of treatment – time since onset –, audiometric curve type and objective vertigo). Audiometric results were evaluated according to Siegel’s criteria. In patients treated also with hyperbaric oxygen therapy we observed complete resolution in 44.1% of the patients, partial resolution in 37.2%, slight improvement in 10.5% and no improvement in 8.2% of the patients. This resolution pattern was significantly different from that observed in the patients treated only with medical therapy. The factors associated with a better prognosis were young age, rapid intervention, upward sloping or pantonal audiometric patterns and the absence of objective vertigo. Gender appeared to be an insignificant factor. Medical treatment associated with hyperbaric oxygen therapy gives better results in terms of hearing gain compared to exclusive medical treatment.

Filippo Ricciardiello, Otorhinolaryngology Unit, Cardarelli Hospital, Naples
Otorhinolaryngology Unit,
Teresa Abate, Otorhinolaryngology Unit, Cardarelli Hospital, Naples
Otorhinolaryngology Unit,
Annalisa Pianese, Otorhinolaryngology Unit, Cardarelli Hospital, Naples
Otorhinolaryngology Unit,
Massimo Mesolella, Otorhinolaryngology Unit, University of Naples Federico II, Naples

Otorhinolaryngology Unit,

Flavia Oliva, Otorhinolaryngology Unit, Cardarelli Hospital, Naples

Otorhinolaryngology Unit, 

Giuseppe Cortese, Department of Anesthesiology, Intensive Care, Hyperbaric Therapy and Pain Therapy, University of Naples Federico II, Naples

Department of Anesthesiology, Intensive Care, Hyperbaric Therapy and Pain Therapy,

Mariano Marmo, Hyperbaric Medic Center, Department of Anesthesiology, Cardarelli Hospital, Naples

Hyperbaric Medic Center, Department of Anesthesiology, 

Romolo Villani, Hyperbaric Medic Center, Department of Anesthesiology, Cardarelli Hospital, Naples

Hyperbaric Medic Center, Department of Anesthesiology, 

Marianna Abate, Department of Biochemistry, Biophysics and General Pathology, University of Campania “L. Vanvitelli”, Naples
Department of Biochemistry Biophysics and General Pathology
Salvatore Mazzone, Otorhinolaryngology Unit, Cardarelli Hospital, Naples
Otorhinolaryngology Unit,
Michele Cavaliere, Otorhinolaryngology Unit, University of Naples Federico II, Naples
Otorhinolaryngology Unit,
Ricciardiello, F., Abate, T., Pianese, A., Mesolella, M., Oliva, F., Ferrise, P., Cortese, G., Marmo, M., Villani, R., Abate, M., Mazzone, S., & Cavaliere, M. (2017). Sudden sensorineural hearing loss: role of hyperbaric oxygen therapy. Translational Medicine Reports, 1(1). https://doi.org/10.4081/tmr.6497

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