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Pharmacological and non-pharmacological treatment options for depression and depressive symptoms in hemodialysis patients

Stefania S. Grigoriou, Christina Karatzaferi, Giorgos K. Sakkas
  • Stefania S. Grigoriou
    Department of Physical Education and Sport Science, University of Thessaly, Trikala; Institute of Research and Technology Thessaly, Centre for Research and Technology-Hellas, Trikala, Greece
  • Christina Karatzaferi
    Department of Physical Education and Sport Science, University of Thessaly, Trikala; Institute of Research and Technology Thessaly, Centre for Research and Technology-Hellas, Trikala, Greece
  • Giorgos K. Sakkas
    Department of Physical Education and Sport Science, University of Thessaly, Trikala; Institute of Research and Technology Thessaly, Centre for Research and Technology-Hellas, Trikala, Greece | gsakkas@med.uth.gr

Abstract

Depression is a mental disorder with a high prevalence among patients with end stage renal disease (ESRD). It is reported that depression afflicts approximately 20-30% of this patient population, being associated, amongst other, with high mortality rate, low adherence to medication and low perceived quality of life. There is a variety of medications known to be effective for the treatment of depression but due to poor adherence to treatment as well as due to the high need for medications addressing other ESRD comorbidities, depression often remains untreated. According to the literature, depression is under-diagnosed and undertreated in the majority of the patients with chronic kidney disease. In the current review the main pharmacological and non-pharmacological approaches and research outcomes for the management of depressive symptoms in hemodialysis patients are discussed.

Keywords

Dialysis; quality of life; survival; exercise; alternative medicine

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Submitted: 2013-07-03 14:19:03
Published: 2015-04-13 00:00:00
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Copyright (c) 2015 Stefania S. Grigoriou, Christina Karatzaferi, Giorgos K. Sakkas

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