Cover Image

Musical hallucinations in elderly patients with visuospatial impairment: two case reports

Chiara Luppi, Francesca Santagata, Margherita Marchetti, Giuliana Bottignole, Pasqualina Sapone, Massimiliano Massaia, Giancarlo Isaia
  • Chiara Luppi
    Department of Geriatrics, AOU Città della salute e della Scienza di Torino, Italy
  • Margherita Marchetti
    Department of Geriatrics, AOU Città della salute e della Scienza di Torino, Italy
  • Giuliana Bottignole
    Department of Geriatrics, AOU Città della salute e della Scienza di Torino, Italy
  • Pasqualina Sapone
    Department of Geriatrics, AOU Città della salute e della Scienza di Torino, Italy
  • Massimiliano Massaia
    Department of Geriatrics, AOU Città della salute e della Scienza di Torino, Italy
  • Giancarlo Isaia
    Unit of Geriatrics and Metabolic Bone Disease, Molinette Hospital and School of Geriatric Medicine, University of Torino, Italy

Abstract

Musical hallucinations are an uncommon type of auditory hallucinations, they widely occur in elderly. Our group analyzed medical history, pharmacological therapy, neuropsychological pattern, audiometric testing, electroencephalogram, cerebral magnetic resonance and cerebral fludeoxyglucose-positron emission tomography (FDG-PET) of two patients. FDGPET showed in both patients hypometabolism pronounced in posterior regions. In particular the medial-inferior temporal cortex and the occipital associative areas were affected. Moreover, neuropsychological pattern suggested a visuospatial-executive deficit, conformed to the occipital involvement. Our reported cases might suggest that musical hallucinations have been arisen from a combination of peripheral and central dysfunction. A further explanation might be that musical hallucinations result from multiple white matter lacunar lesions due to small vascular events. A question is whether musical hallucinations might be primarily associated with occipital areas hypometabolism and visuospatial alterations typically associated with Levy body dementia (LBD).

Keywords

Musical hallucinations; vascular dementia; cognitive decline; elderly; visuospatial impairment.

Full Text:

PDF
HTML
Submitted: 2016-09-15 12:02:35
Published: 2017-01-18 12:58:11
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
839

Views:
PDF
626
HTML
560

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c) 2017 Chiara Luppi, Francesca Santagata, Margherita Marchetti, Giuliana Bottignole, Pasqualina Sapone, Massimiliano Massaia, Giovanni Carlo Isaia

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
 
© PAGEPress 2008-2017     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185