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DOI: http://dx.doi.org/10.4081/eye.2011.e12

Optic disc parameters in manifest and suspected glaucoma

Peter Wanger, Lucian Vancea, Lene Martin

Abstract


Structure and function measurements are important in glaucoma management. Digital fundus photography has become a standard procedure and the Heidelberg Retina Tomograph (HRT), commonly used by glaucoma specialists, provides a glaucoma probability score (GPS). The visual field index (VFI) is a novel statistic, aiming to facilitate follow-up of glaucoma patients. The aim of this study was to compare the results from the digital analysis of fundus photographs with HRT measurements including GPS and VFI in patients with ocular hypertension, suspect glaucoma or glaucoma, and if possible define an optic disc index, useful in glaucoma diagnosis. Fifty-eight consecutive patients from a glaucoma service were included. Optic disc parameters (disc and cup areas) were measured on digital fundus photographs, using a semi-automatic method, and compared with the GPS from the HRT and the VFI from standard automated perimetry. A significant relationship was observed between the GPS group classification (normal, borderline, or abnormal) and VFI classification (normal or abnormal), both when the GPS borderline group was regarded as normal (P = 0.0038 Fisher test) and as abnormal (P=0.0179, kappa = 0.33). No significant relationship was observed between VFI and optic disc parameters. The threedimensional information in the GPS appears to be more related to visual function, as measured by VFI, than the planimetric measures of the optic disc.

Keywords


digital fundus photography, optic disc, heidelberg retina tomograph, glaucoma probability score, visual field index.

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Submitted: 2011-04-13 22:37:45
Published: 2011-12-01 11:39:02
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References


Sheidow PT, Hooper P. Prospective evaluation of digital non-stereo color fundus photography as a screening tool in age-related macular degeneration. Am J Ophthalmol 2005;139:455-61.

O'Leary N, Crabb DP, Mansberger SL, et al. Glaucomatous progression in series of stereoscopic photographs and Heidelberg retina tomograph images. Arch Ophthalmol 2010;128:560-8.

Laemmer R, Schroeder S, Martus P, et al. Quantification of neuroretinal rim loss using digital planimetry in long-term follow-up of normals and patients with ocular hypertension. J Glaucoma 2007;16:430-6.

Chauhan BC, Hutchison DM, Artes PH, et al. Optic disc progression in glaucoma: comparison of confocal scanning laser tomography to optic disc photographs in a prospective study. Invest Ophthalmol Vis Sci 2009;50:1682-91.

Bartling H, Wanger P, Martin L. Measurement of optic disc parameters on digital fundus photographs – algorithm development and evaluation. Acta Ophthalmol Scand 2008;86:837-41.

Heijl A, Mölder H. Optic disc diameter influences the ability to detect glaucomatous disc damage. Acta Ophthalmol (Copenh) 1993;71:122-9.

Hoesl LM, Mardin CY, Horn FK, et al. Influence of glaucomatous damage and optic disc size on glaucoma detection by scanning laser tomography. J Glaucoma 2009;18:385-9.

RAND Study Group. For which glaucoma suspects is it appropriate to initiate treatment? Ophthalmology 2009;116:710-16.

Strouthidis NG, Garway-Heath DF. New developments in Heidelberg retina tomograph for glaucoma. Curr Opin Ophthalmol 2008;19:141-8.

Williams TD. Elliptical features of the human optic nerve head. Am J Optom Physiol Opt 1987;64:172-8.

Wakakura M, Alvarez E. A simple clinical method of assessing patients with optic nerve hypoplasia. The disc-macula distance to disc diameter ratio (DM/DD). Acta Ophthalmol (Copenh) 1987;65:612-7.

Williams TD, Wilkingson JM. Position of the fovea centralis with respect to the optic nerve head. Optom Vis Sci 1992;69;369-77.

Mok KH, Lee VW. Disk-to-macula distance to disc-diameter ratio for optic disc size estimation. J Glaucoma 2002;11:392-5.

Bengtsson B, Heijl A. A visual field index for calculation of glaucoma rate of progression. Am J Ophthalmol 2008;145:343-53.

Alencar LM, Bowd C, Weinreb RN, et al. Comparison of HRT-3 glaucoma probability score and subjective stereophotograph assessment for prediction of progression in glaucoma. Invest Ophthalmol Vis Sci 2008;49:1898-906.


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