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Role of ventricular tachycardia ablation in arrhythmogenic right ventricular cardiomyopathy

Alberto Cipriani, Riccardo Bariani, Manuel De Lazzari, Federico Migliore, Carlo Angheben, Maurizio Del Greco, Domenico Corrado, Alessandro Zorzi
  • Alberto Cipriani
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
  • Riccardo Bariani
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
  • Manuel De Lazzari
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
  • Federico Migliore
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
  • Carlo Angheben
    Division of Cardiology, Santa Maria del Carmine Hospital, Rovereto (TN), Italy
  • Maurizio Del Greco
    Division of Cardiology, Santa Maria del Carmine Hospital, Rovereto (TN), Italy
  • Domenico Corrado
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy | domenico.corrado@unipd.it
  • Alessandro Zorzi
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by progressive fibro-fatty replacement of the myocardium that represents the substrate for recurrent sustained ventricular tachycardia (VT). These arrhythmias characterize the clinical course of a sizeable proportion of patients and have significant implications for their quality of life and long-term prognosis. Antiarrhythmic drugs are often poorly tolerated and usually provide incomplete control of arrhythmia relapses. Catheter ablation is a potentially effective strategy to treat frequent VT episodes and ICD shocks in ARVC patients. The aims of this review are to discuss the electrophysiological and electroanatomic substrates of ventricular tachycardia in patients with ARVC and to analyze the role of catheter ablation in their management with particular reference to selection of patients, technical issues, potential complications and outcomes.

Keywords

Endocardial voltage mapping; electrophysiology; ventricular tachycardia; sudden death.

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Submitted: 2017-07-05 14:48:23
Published: 2017-11-07 13:00:39
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Copyright (c) 2017 Alberto Cipriani, Riccardo Bariani, Manuel De Lazzari, Federico Migliore, Carlo Angheben, Maurizio Del Greco, Domenico Corrado, Alessandro Zorzi

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