Prolonged antibiotic therapy increases risk of infection after transrectal prostate biopsy: A case report after pancreasectomy and review of the literature


Submitted: January 23, 2015
Accepted: January 23, 2015
Published: December 30, 2014
Abstract Views: 1595
PDF: 952
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Authors

  • Guevar Maselli Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Giacomo Tucci Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Daniele Mazzaferro Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Asim Ettamimi Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Giulia Sbrollini Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Marco Cordari Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Gaetano Donatelli Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Andrea Benedetto Galosi Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
Infection due to prostate biopsy afflicted more than 5% of patients and is the most common reason for hospitalization. A large series from US SEER-Medicare reported that men undergoing biopsy were 2.26 times more likely to be hospitalized for infectious complications within 30 days compared with randomly selected controls. The factors predicting a higher susceptibility to infection remain largely unknown but some authors have higlighted in the etiopathogenesis the importance of the augmented prevalence of ciprofloxacin resistant variant of bacteria in the rectum flora. We present one case of sepsis after transrectal prostate biopsy in a patient with history of pancreatic surgery. Based on our experience patients candidated to prostate biopsy with transrectal technique with history of recent major surgery represent an high risk category for infective complication. Also major pancreatic surgery should be consider an high risk category for infection. A transperineal approach and preventive measures (such as rectal swab) should be adopted to reduce biopsy driven infection.

Maselli, G., Tucci, G., Mazzaferro, D., Ettamimi, A., Sbrollini, G., Cordari, M., Donatelli, G., & Galosi, A. B. (2014). Prolonged antibiotic therapy increases risk of infection after transrectal prostate biopsy: A case report after pancreasectomy and review of the literature. Archivio Italiano Di Urologia E Andrologia, 86(4), 387–388. https://doi.org/10.4081/aiua.2014.4.387

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