First case of bilateral, synchronous anaplastic variant of spermatocytic seminoma treated with radical orchifunicolectomy as single approach: Case report and review of the literature


Submitted: March 28, 2014
Accepted: March 28, 2014
Published: March 28, 2014
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Authors

  • Giorgio Gentile Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Francesca Giunchi Department of Pathology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Riccardo Schiavina Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Alessandro Franceschelli Andrology Unit, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Marco Borghesi Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Ziv Zukerman Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Matteo Cevenini Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Valerio Vagnoni Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Daniele Romagnoli Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Fulvio Colombo Andrology Unit, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Giuseppe Martorana Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
  • Eugenio Brunocilla Department of Urology, Azienda Ospedaliero-Universitaria Policlinico S.Orsola-Malpighi, Bologna, Italy.
Spermatocytic Seminoma (SS) is less common than the Classic variant, as its incidence ranges between 1.3% and 2.3% of all seminomas. Generally SS is diagnosed in men older than 50 years. The Anaplastic variant of Spermatocytic Seminoma is characterized by an earlier onset when compared to SS, but a benign behavior in spite of its histological patterns similar to Classic Seminoma. We reported the first case of bilateral, largest and synchronous Anaplastic Spermatocytic Seminoma, in a patient treated with radical orchifunicolectomy alone and with long-term follow-up. The currently available data show that Anaplastic SS reveals a clinically benign behavior, and no distant metastases have been reported so far. A close surveillance after surgery could be considered a valid option in the management of this rare testicular neoplasm.

Gentile, G., Giunchi, F., Schiavina, R., Franceschelli, A., Borghesi, M., Zukerman, Z., Cevenini, M., Vagnoni, V., Romagnoli, D., Colombo, F., Martorana, G., & Brunocilla, E. (2014). First case of bilateral, synchronous anaplastic variant of spermatocytic seminoma treated with radical orchifunicolectomy as single approach: Case report and review of the literature. Archivio Italiano Di Urologia E Andrologia, 86(1), 41–42. https://doi.org/10.4081/aiua.2014.1.41

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